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Table 2 Nutritional requirements for production of 3-HP from sugar monomers

From: Metabolic engineering to improve production of 3-hydroxypropionic acid from corn-stover hydrolysate in Aspergillus species

Host

Carbon source

Titer (g/L)

Rate (g/Lh)

Yield (g/g)

NH4 (g/L)

PO4 (g/L)

Additives

pH

Refs.

E. coli

Glucose (pure)

40.6

0.56

0.19

3.0

9.8

Vitamins, IPTG

7.0, NH3

[65]

S. pombe

Glucose (pure)

11.2

0.12

0.12

5.0

2.2

Vitamins

5.0, NH3

[50]

S. cerevisiae

Glucose (pure)

13.7

0.17

0.17

15.0

6.0

Vitamins

5.0, NaOH

[27]

S. cerevisiae

Glucose (pure)

9.2

0.13

0.09

15.0

6.0

Vitamins

3.5, NaOH

[27]

S. cerevisiae

Glucose (pure)

9.8

0.09

0.13

15.0

6.0

Vitamins

5.0, NaOH

[25]

S. cerevisiae

Xylose (pure)

7.4

0.06

0.29

15.0

3.0

Vitamins

5.0, NaOH

[51]

C. glutamicum

Glucose/xylose (pure)

54.8

0.76

0.49

24.0

2.5

Vitamins, IPTG, corn steep liquor

7.2, NH3

[52]

E. coli

Glucose/xylose (pure)

37.6

0.63

0.17

4.0

13.5

Vitamins, IPTG, yeast extract

6.8, NH3

[53]

E. coli

Glucose/xylose (pure)

53.7

0.63

0.13

4.0

13.5

Vitamins, IPTG, yeast extract

6.8, NH3

[54]

E. coli

Glucose/xylose (pure)

29.7

0.54

0.36

4.0

13.5

Vitamins, IPTG, yeast extract

6.8, NH3

[55]

A. niger

Glucose/xylose (hydrolysate)

36.0

0.21

0.48

2.4

0.1

–

 <2.0, no control

This work