Fig. 1

Multi-modular architecture of the TwCel5-6. A Display of the full-length gene encoding protein TwCel5-6 is composed of a signal peptide (SP), a glycosyl hydrolase 5 (GH5), three family 10 cellulose-binding modules (CBMs), and a glycosyl hydrolase 6 (GH6) catalytic domains, respectively. B Alphafold2 predicted structure of TwCel5-6; the unstructured linkers, CBM10s and the GH5 and GH6 catalytic modules are colored grey, green, blue, and magenta, respectively. C Details of the first CBM10 module showing the disulphide bridge (black arrow) connecting the linkers that enter and exit the module