Fig. 3
From: Engineering yeast mitochondrial metabolism for 3-hydroxypropionate production
3-HP production with increased NADPH synthesis. A Overexpression of NADPH generating enzymes in the strain NmC2. NmC2 pALD4, the strain NmC2 harboring pALD4; NmC2 MAE1, the strain NmC2 with MAE1 overexpressed; NmC2 pPOS5, the strain NmC2 harboring pPOS5; NmC2 IDP1, the strain NmC2 with IDP1 overexpressed; N2IP, the strain NmC2 with IDP1 and POS5 overexpressed. B Overexpression of NADPH generating enzymes in the strain NmC3. N3IP, the strain NmC3 with IDP1 and POS5 overexpressed; N3IP pMaeA*, the strain N3IP harboring pMaeA*. The cultivations were performed in biologically triplicate and error bars represent ± standard errors. Statistical analysis was performed using one-tailed Student’s t test (*p < 0.05, **p < 0.01)