Fig. 6

Transcriptomic profile of ΔlaeA strain grown on Avicel. a Principal component analysis of RNA-Seq data from the WT, and ΔlaeA strains grown on 2% Avicel for 2, 4, and 6 days. b Total RPKM value of CAZyme genes from RNA-seq data in WT and ΔlaeA strains. c Relative mRNA abundance of all CAZyme genes in ΔlaeA mutant vs WT when growth on cellulose for 2 or 4 d. Genes showing significant differential expression are shown in turquoise (based on the adjusted p value). Cellulase genes showing differential expression are shown in red. d Heatmap analysis of expression levels of transcription factors regulating cellulase production in strains WT and ΔlaeA. Positive regulator (top); negative regulator (bottom)