Table 2 Mutations identified in evolved strains CALE1 and CALE2
Strain | Position | Type | Locus tag | Reference | Mutation | Amino acid change | Description |
|---|---|---|---|---|---|---|---|
CALE 1 | 242720 | Nonsynonymous SNV | CG_211 | G | T | A104D | Putative membrane protein |
1320434 | Intergenic SNV | CG_1192 (upstream dist = 176 bp) | C | T | Copper resistance protein | ||
1998826 | Nonsynonymous SNV | CG_1807 | G | A | R370H | Excinuclease ABC subunit A | |
2123755 | Synonymous SNV | CG_1940 | T | C | G194G | ABC transporter permease | |
2325348 | Nonsynonymous SNV | CG_2122 | A | C | M1R | Mycothiol system anti-sigma-R factor | |
2351992 | Nonsynonymous SNV | CG_2149 | A | T | I136F | Cell wall biosynthesis protein | |
2404985 | Nonsynonymous SNV | CG_2185 | G | T | G86V | Sulfur transferase | |
2448523 | Synonymous SNV | CG_2223 | T | C | D96D | Hypothetical protein | |
2609654 | Synonymous SNV | CG_2388 | G | A | R157R | Elongation factor Tu | |
649723 | Intergenic InDel | CG_566, CG_567 (upstream dist = 76 bp) | G | Putative arsenite efflux pump/IS6 family transposase | |||
CALE 2 | 242720 | Nonsynonymous SNV | CG_211 | G | T | A104D | Putative membrane protein |
782863 | Synonymous SNV | CG_695 | C | T | V18V | IclR family transcriptional regulator PcaR | |
1300584 | Nonsynonymous SNV | CG_1170 | G | A | H339Y | RNA polymerase sigma factor SigA | |
1525317 | Nonsynonymous SNV | CG_1375 | A | G | R75G | Sec-independent protein secretion pathway component | |
84404 | Intergenic InDel | CG_74 (upstream dist = 30 bp) | T | IS1634 family transposase | |||
649723 | Intergenic InDel | CG_566, CG_567 (upstream dist = 76 bp) | GG | Putative arsenite efflux pump/IS6 family transposase |