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Fig. 4 | Biotechnology for Biofuels and Bioproducts

Fig. 4

From: Transcriptomic and metabolomic analyses revealed regulation mechanism of mixotrophic Cylindrotheca sp. glycerol utilization and biomass promotion

Fig. 4

Comparative transcriptomic analysis between mixotrophy and autotrophy at point A. a KEGG enrichment analysis. Pathways with q < 0.05 are considered significantly enriched; b gene set enrichment analysis (GSEA). KEGG pathways with q < 0.05 are considered significantly enriched and corresponding normalized enrichment score (NES) is noted. RES: running enrichment score; RLM: ranked list metric; c protein–protein interaction network of genes in significantly enriched KEGG pathways in GSEA with top ten hub genes, evaluated by betweenness, in the center. Nos. 1–10 represent glutamate-tRNA ligase, isoleucine-tRNA ligase, anthranilate synthase, phenylalanine-tRNA ligase beta subunit, arogenate/prephenate dehydratase, aspartate aminotransferase, aspartate transaminase, tyrosine-tRNA ligase, cytoplasmic leucine-tRNA ligase and chloroplastic/mitochondrial leucine-tRNA ligase, respectively. Analysis was carried out for biological triplicates

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