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Fig. 5 | Biotechnology for Biofuels and Bioproducts

Fig. 5

From: Transcriptomic and metabolomic analyses revealed regulation mechanism of mixotrophic Cylindrotheca sp. glycerol utilization and biomass promotion

Fig. 5

Comparative transcriptomic analysis between mixotrophy and autotrophy at point C. a KEGG enrichment analysis. Pathways with q < 0.05 are considered significantly enriched; b representative gene set enrichment analysis (GSEA). Pathways with q < 0.05 are considered significantly enriched and corresponding normalized enrichment score (NES) is noted; RES: running enrichment score; RLM: ranked list metric; c protein–protein interaction network of genes in significantly enriched KEGG pathways in GSEA analysis with top ten hub genes, evaluated by betweenness, in the center. Nos. 1–10 represent 26S proteasome non-ATPase regulatory subunit 11 homolog, RNA polymerase III subunit Rpc25, CDK-activating kinase assembly factor MAT1, nucleolar protein 5–2, nucleolar protein 5–2, proliferating cell nuclear antigen, 26S proteasome regulatory subunit 6B homolog, replication protein A 32-kDa subunit B, replication protein A 70-kDa DNA-binding subunit A and carbamoyl-phosphate synthase large chain. Analysis was carried out for biological triplicates

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