Fig. 1

Proposed Embden–Meyerhof–Parnas pathway and alternative pentose phosphate pathway in C. thermocellum. Phosphoenolpyruvate can be converted to pyruvate either by the pyruvate phosphate dikinase (PPDK) or alternatively via the malate shunt pathway. GK glucokinase, PGI phosphate glucose isomerase, GAPDH glyceraldehyde-3-phosphate dehydrogenase, PGK phosphoglycerate kinase, PGM phosphoglycerate mutase, ENO enolase, PEPCK phosphoenolpyruvate carboxykinase, MDH malate dehydrogenase, MalE malic enzyme, OAADC oxaloacetate decarboxylase, TKT transketolase