Fig. 6

Expression profiles of genes involved in pyruvate metabolism (A), tryptophan metabolism (B), tyrosine metabolism (C), leucine metabolism (D), isoleucine metabolism (E), lysine metabolism (F) and fatty acid synthesis (G) pathway in C. zofingiensis based on transcriptomic analyses. PDHA: pyruvate dehydrogenase E1 component alpha subunit; PDHB: pyruvate dehydrogenase E1 component beta subunit; PDC: pyruvate decarboxylase; PDHC: pyruvate dehydrogenase E2 component; BCAT: branched-chain amino acid aminotransferase; BCKDH: 2-oxoisovalerate dehydrogenase; ACADs: acyl-CoA dehydrogenase; ECH: enoyl-CoA hydratase; ACAA1: acetyl-CoA acyltransferase 1; AST: aspartate aminotransferase; PAT: bifunctional aspartate aminotransferase and glutamate/aspartate-prephenate aminotransferase; hisC: histidinol-phosphate aminotransferase; HPPD: 4-hydroxyphenylpyruvate dioxygenase; HGD: homogentisate 1,2-dioxygenase; MCC: 3-methylcrotonyl-CoA carboxylase; AUH: methylglutaconyl-CoA hydratase; HMGCL: hydroxymethylglutaryl-CoA lyase; KMO: kynurenine 3-monooxygenase; OGDH: 2-oxoglutarate dehydrogenase; DLD: dihydrolipoyl dehydrogenase; gabD: uccinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase; ACACA: acetyl-CoA carboxylase1; ACCase: acetyl-CoA carboxylase; FASN: fatty acid synthase; fabD: [acyl-carrier-protein] S-malonyltransferase; fabF: 3-oxoacyl-[acyl-carrier-protein] synthase II; fabH: 3-oxoacyl-[acyl-carrier-protein] synthase III; fabG: 3-oxoacyl-[acyl-carrier protein] reductase; fabZ: 3-hydroxyacyl-[acyl-carrier-protein] dehydratase; fabI: enoyl-[acyl-carrier protein] reductase I; MECR: mitochondrial trans-2-enoyl-CoA reductase. (The expression levels of each gene were plotted on a heat map using the log2FC values in comparison to the control group; the * denoted a significant difference from the control group, p ≤ 0.05)