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Fig. 1 | Biotechnology for Biofuels and Bioproducts

Fig. 1

From: The adc1 knockout with proC overexpression in Synechocystis sp. PCC 6803 induces a diversion of acetyl-CoA to produce more polyhydroxybutyrate

Fig. 1

Overview of the polyamine-proline-glutamate pathways connected to the tricarboxylic acid (TCA) cycle and related biosynthetic pathways of polyhydroxybutyrate (PHB), and glycogen in cyanobacterium Synechocystis sp. PCC 6803. Abbreviations of genes are: acc, a multisubunit acetyl-CoA carboxylase; ach, acetyl-CoA hydrolase; ackA, acetate kinase; acs, acetyl-CoA synthase; adc, arginine decarboxylase; argD, N-acetylornithine aminotransferase; gad, glutamate decarboxylase; gdhA, glutamate dehydrogenase; glgC, ADP-glucose pyrophosphorylase; glgX, glycogen debranching enzyme; gltA, citrate synthase; plsX, fatty acid/phospholipid synthesis protein; phaA, β-ketothiolase; phaB, acetoacetyl-CoA reductase; phaC and phaE, the heterodimeric PHB synthase; proA, gamma-glutamyl phosphate reductase; proC, Δ1pyrroline-5-carboxylate reductase; pta, phosphotransacetylase; putA, proline oxidase; speB1, arginase; speB2, agmatinase. Abbreviations of intermediates are: FASII, fatty acid synthesis type II; GABA, gamma-aminobutyric acid; GOGAT, glutamate synthase; G6P, glucose-6-phosphate; GS, glutamine synthetase; 3-PGA, 3-phosphoglycerate; PHB, polyhydroxybutyrate

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