Table 2 Contents of some metabolites related to polyamine-proline-glutamate pathway. Cells were grown in various media for 7 days (means ± S.D., n = 3). The statistical difference in the data between the values of WT and the engineered strain is represented by an asterisk at * p < 0.05

12.4 ± 0.8

7.2 ± 0.2

5.4 ± 0.3

8.9 ± 0.6*

3.8 ± 0.4*

5.2 ± 0.4

14.3 ± 0.5*

6.6 ± 0.1*

8.4 ± 0.5*

10.9 ± 0.2*

6.1 ± 0.2*

4.6 ± 0.1*

37.8 ± 3.0

21.2 ± 2.0

48.5 ± 4.0

13.2 ± 0.9*

81.5 ± 5.0*

19.0 ± 0.6*

61.1 ± 5.4*

180.4 ± 11.0*

130.0 ± 10.0*

41.5 ± 3.0

147.3 ± 12.0*

232.5 ± 15.0*

415.2 ± 30.0

38.8 ± 3.0

58.3 ± 3.0

931.0 ± 20.0*

43.8 ± 3.0

159.0 ± 8.0*

747.0 ± 40.0*

287.0 ± 20.0*

294.8 ± 15.0*

1784 ± 70.0*

193.5 ± 10.0*

253.9 ± 10.0*

338.0 ± 10.0

294.8 ± 9.0

174.6 ± 5.0

226.7 ± 8.0*

253.0 ± 8.0*

190.4 ± 10.0

144.4 ± 8.0*

88.5 ± 6.0*

112.1 ± 6.0*

89.8 ± 5.0*

159.5 ± 10.0*

115.0 ± 5.0*