Table 2 Kinetic parameters of HpaB mutants in different studies
From: Exploring the role of flavin-dependent monooxygenases in the biosynthesis of aromatic compounds
Enzymes | Variant | Substrates | Products | Convertion rate (%) | References |
|---|---|---|---|---|---|
AbHpaB | Wild type | Tyramine | Dopamine | ND | [59] |
| Â | R293A | Â | Â | 7 | Â |
| Â | R263D | Â | Â | 57 | Â |
| Â | Wild type | 4-Coumaric acid | 3,4,5-THCA | 7.5 | [60] |
| Â | Y398S | Â | Â | 23.2 | Â |
| Â | Wild type | Octopamine | Norepinephrine | ND | [61] |
| Â | R263D/Y398D | Â | Â | 13 | Â |
EcHpaBC | Wild type | Tyrosine | L-Dopa | 1.01 | [63] |
| Â | 23F9-M4 | Â | Â | 95.5 | Â |
EcHpaBC | Wild type | Tyrosol | Hydroxytyrosol | 4.87 | [65] |
| Â | Â | Tyramine | Dopamine | 0.1 | Â |
| Â | S210T/A211L/Q212E | Tyrosol | Hydroxytyrosol | 95.2 | Â |
| Â | Â | Tyramine | Dopamine | 2.15 | Â |
| Â | A211G / Q212Y | Tyrosol | Hydroxytyrosol | 7.23 | Â |
| Â | Â | Tyramine | Dopamine | 90.54 | Â |
| Â | S210T/A211M/Q212G | Tyrosol | Hydroxytyrosol | 97.33 | Â |
| Â | Â | Tyramine | Dopamine | 45.51 | Â |