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Fig. 5 | Biotechnology for Biofuels

Fig. 5

From: Integrated omics analyses reveal the details of metabolic adaptation of Clostridium thermocellum to lignocellulose-derived growth inhibitors released during the deconstruction of switchgrass

Fig. 5

Valine, leucine, and isoleucine yield precursors for branched-chain fatty acid synthesis The red arrow in the pathway refers to the significant enzymes that belong to clusters 3 or 4. The green arrow refers to the significant enzymes that belong to clusters 1 and 2. The blue arrow refers to the enzymes that were detected in mass spectrometry but were not significantly changing over time. 1. Acetolactate synthase Cthe_2516, 2517, 2714; 2. Ketol-acid reductoisomerase Cthe_2518; 3. Dihydroxy-acid dehydratase Cthe_2713; 4. 2-Isopropylmalate synthase Cthe_1391, 2519; 5. 3-Isopropylmalate dehydratase Cthe_2210, 2211; 6. 3-Isopropylmalate dehydrogenase Cthe_2209; 7. Branched-chain amino acid aminotransferase Cthe_0856; 8. Branched-chain keto acid dehydrogenase Cthe_0547*—possible new functional annotation [52]—Fatty acid synthase enzymes (Fab H,G,J,I reported in Additional File 10: Table S7

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Biotechnology for Biofuels and Bioproducts

ISSN: 2731-3654

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