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Table 1 Cellulosomal and non-cellulosomal carbohydrate-active enzymes showing significant temporal dynamics

From: Integrated omics analyses reveal the details of metabolic adaptation of Clostridium thermocellum to lignocellulose-derived growth inhibitors released during the deconstruction of switchgrass

Locus tag

Protein name

Protein function

19 h

43 h

91 h

187 h

p value (<0.05)

Cluster

Non-catalytic cellulosomal proteins

 Cthe_3079

Orf2p

Cellulosome anchoring protein, cohesin region

5.18

5.57

6.46

6.99

2.27E−05

C4

 Cthe_0452

OlpC

Cellulosome anchoring protein, cohesin region

2.32

–1.06

–0.76

–0.58

1.41E−04

C2

 Cthe_3077

CipA

Cellulosome anchoring protein, cohesin region

9.61

9.81

10.14

10.6

5.32E−04

C4

 Cthe_3080

OlpA

Cellulosome anchoring protein, cohesin region

5.73

6.51

7.17

7.44

4.01E−03

C4

 Cthe_1307

SdbA

Cellulosome anchoring protein, cohesin region

4.92

4.06

4.08

3.84

8.68E−03

C2

 Cthe_3078

OlpB

Cellulosome anchoring protein, cohesin region

7.4

7.66

8.17

8.02

1.24E−02

C4

Cellulosomal cellulase genes

 Cthe_0044

CseP

Cellulosome enzyme, dockerin type I

–1.94

–2.12

0.12

2.68

4.69E−04

C3

 Cthe_2972

XynA

Glycoside hydrolase, family 11

3.96

4.44

5.74

6.71

4.86E−04

C3

 Cthe_0912

XynY

Glycoside hydrolase, family 10

–1.36

–3.06

0.54

1.98

5.88E−04

C3

 Cthe_3132

Cthe_3132

Cellulosome enzyme, dockerin type I

–1.56

0.49

1.92

2.88

6.80E−04

C3

 Cthe_1963

XynZ

Glycoside hydrolase, family 10

2.39

2.63

3.75

4.73

9.20E−04

C3

 Cthe_2147

CelO

Glycoside hydrolase, family 5

–2.25

−2.4

0.81

1.54

2.05E−03

C3

 Cthe_0239

Cthe_0239

Cellulosome enzyme, dockerin type I

1.43

1.82

2.7

3.56

2.10E−03

C3

 Cthe_0745

CelW

Glycoside hydrolase, family 9

0.23

1.11

2.14

2.16

2.47E−03

C3

 Cthe_1472

CelH

Carbohydrate binding family 11

–0.69

–2.18

0.23

1.32

3.22E−03

C3

 Cthe_0797

CelE

Glycoside hydrolase, family 5

2.46

2.4

3.05

3.91

9.96E−03

C4

 Cthe_2590

XynD

Glycoside hydrolase, family 10

−0.6

–0.27

1.7

2.65

1.06E−02

C3

 Cthe_3141

Cthe_3141

Lipolytic enzyme, G-D-S-L

0.14

–0.36

1.96

2.58

1.12E−02

C3

 Cthe_0433

Cthe_0433

Glycoside hydrolase, family 9

2.41

1.08

2.63

3.49

1.41E−02

C4

 Cthe_0043

CelN

Glycoside hydrolase, family 9

1.37

1.64

2.35

2.91

1.55E−02

C4

 Cthe_1806

Cthe_1806

Cellulosome enzyme, dockerin type I

1.55

1.1

2.22

2.8

1.81E−02

C4

 Cthe_0625

CelQ

Glycoside hydrolase, family 9

2.5

1.46

2.29

2.43

1.93E−02

C4

 Cthe_0274

CelP

Glycoside hydrolase, family 9

1.59

1.88

2.68

3.11

2.68E−02

C3

 Cthe_0190

Cthe_0190

Proteinase inhibitor I4, serpin

1.47

2.05

3.57

4.36

3.15E−02

C3

 Cthe_0258

Doc258

Cellulosome enzyme, dockerin type I

2.58

2.29

3.52

3.82

3.92E−02

C4

Free enzyme system

 Cthe_2809

LicA

Glycoside hydrolase, family 16

3.53

4.03

4.9

5.32

8.76E−04

C4

 Cthe_1471

Cthe_1471

Glycoside hydrolase, family 5

−2

–0.29

–0.94

1.31

1.45E−02

C3

 Cthe_1256

bglB

Glycoside hydrolase, family 3-like protein

1.5

3.17

2.46

2.17

2.11E−02

C4

 Cthe_3063

Cthe_3063

Acetyl xylan esterase

–1.18

–1.36

–1.09

0.71

2.63E−02

C4

 Cthe_2989

Cdp

Glycosyltransferase 36

2.95

3.61

3.42

3.29

3.87E−02

C4

  1. The values at the different time points are log2 (NSAF) values