Fig. 8From: A seven-gene cluster in Ruminiclostridium cellulolyticum is essential for signalization, uptake and catabolism of the degradation products of cellulose hydrolysisModel for cellodextrins utilization by R. cellulolyticum. The cellulosome is depicted in light (CipC)/dark (enzymes) brown, bound to cellulose chains, and releasing cellodextrins like cellobiose. The latter is recognized by CuaD (orange) bound to CuaS (purple) and signal is transmitted to the regulator CuaR (light blue) which subsequently induces the expression of the genes cuaABC and cbpA. The ABC transporter captures a large range of cellodextrins from the environment and transport them in the cytoplasm where the cellobiose phosphorylase CbpA cleaves the cellobiose in glucose and G1-P. Other cellodextrins might be degraded by other unknown cellodextrin phosphorylases or β-glucosidase. Unknown proteins like NBD and enzymes degrading intracellular dextrins are depicted in grayBack to article page