Fig. 1
From: Modulating redox metabolism to improve isobutanol production in Shimwellia blattae
Metabolic pathway for isobutanol production in S. blattae (p424IbPSO) and new constructions (1 and 2). Pyruvate (2x) means that two pyruvate molecules are required to synthesize one 2-acetolactate molecule; AlsS, acetolactate synthase; IlvC, acetohydroxy acid isomeroreductase, IlvD, dihydroxyacid dehydratase; Kdc, 2-ketoacid decarboxylase; YqhD, alcohol dehydrogenase (endogenous). In new construction 1, AdhA, alcohol dehydrogenase (L. lactis) and in new construction 2, PntAB, nicotinamide nucleotide transhydrogenase (E. coli)