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  1. Yeast was the first microorganism used by mankind for biotransformation processes that laid the foundations of industrial biotechnology. In the last decade, Pichia pastoris has become the leading eukaryotic host ...

    Authors: Burcu Gündüz Ergün, Kübra Laçın, Buse Çaloğlu and Barış Binay
    Citation: Biotechnology for Biofuels and Bioproducts 2022 15:150
  2. During the kraft process to obtain cellulosic pulp from wood, most of the lignin is removed by high-temperature alkaline cooking, released in the black liquors and usually incinerated for energy. However, kraf...

    Authors: David Rodríguez-Escribano, Rocío Pliego-Magán, Felipe de Salas, Pablo Aza, Patrizia Gentili, Petri Ihalainen, Thomas Levée, Valérie Meyer, Michel Petit-Conil, Sandra Tapin-Lingua, Michael Lecourt and Susana Camarero
    Citation: Biotechnology for Biofuels and Bioproducts 2022 15:149
  3. Miscanthus, a C4 member of Poaceae, is a promising perennial crop for bioenergy, renewable bioproducts, and carbon sequestration. Species of interest include nothospecies M. x giganteus and its parental species M...

    Authors: Anthony Trieu, Mohammad B. Belaffif, Pradeepa Hirannaiah, Shilpa Manjunatha, Rebekah Wood, Yokshitha Bathula, Rebecca L. Billingsley, Anjali Arpan, Erik J. Sacks, Thomas E. Clemente, Stephen P. Moose, Nancy A. Reichert and Kankshita Swaminathan
    Citation: Biotechnology for Biofuels and Bioproducts 2022 15:148
  4. Platform chemicals and polymer precursors can be produced via enzymatic pathways starting from lignocellulosic waste materials. The hemicellulose fraction of lignocellulose contains aldopentose sugars, such as d-...

    Authors: Yaxin Ren, Veikko Eronen, Martina Blomster Andberg, Anu Koivula and Nina Hakulinen
    Citation: Biotechnology for Biofuels and Bioproducts 2022 15:147
  5. Whole-cell biotransformation is a promising emerging technology for the production of chemicals. When using heterotrophic organisms such as E. coli and yeast as biocatalysts, the dependence on organic carbon sour...

    Authors: Gábor Szilveszter Tóth, Vilja Siitonen, Lauri Nikkanen, Lucija Sovic, Pauli Kallio, Robert Kourist, Sergey Kosourov and Yagut Allahverdiyeva
    Citation: Biotechnology for Biofuels and Bioproducts 2022 15:146
  6. Lignocellulosic resources are promising feedstocks for the manufacture of bio-based products and bioenergy. However, the inherent recalcitrance of biomass to conversion into simple sugars currently hinders the...

    Authors: Chien-Yuan Lin, Gina M. Geiselman, Di Liu, Harsha D. Magurudeniya, Alberto Rodriguez, Yi-Chun Chen, Venkataramana Pidatala, Faride Unda, Bashar Amer, Edward E. K. Baidoo, Shawn D. Mansfield, Blake A. Simmons, Seema Singh, Henrik V. Scheller, John M. Gladden and Aymerick Eudes
    Citation: Biotechnology for Biofuels and Bioproducts 2022 15:145
  7. There is a growing global need to transition from a fossil-based to a bio-based economy to produce fuels, chemicals, food, and materials. In the specific context of industrial biotechnology, a successful trans...

    Authors: Samir Meramo, Peter Fantke and Sumesh Sukumara
    Citation: Biotechnology for Biofuels and Bioproducts 2022 15:144
  8. The overall goal of the present study is to investigate the economics of an integrated biorefinery converting hybrid poplar into jet fuel, xylitol, and formic acid. The process employs a combination of integra...

    Authors: Gabriel V. S. Seufitelli, Hisham El-Husseini, Danielle U. Pascoli, Renata Bura and Richard Gustafson
    Citation: Biotechnology for Biofuels and Bioproducts 2022 15:143
  9. The filamentous fungus Trichoderma reesei is extensively used for the industrial-scale cellulase production. It has been well known that the transcription factor Xyr1 plays an important role in the regulatory net...

    Authors: Linjing Shen, Aiqin Yan, Yifan Wang, Yubo Wang, Hong Liu and Yaohua Zhong
    Citation: Biotechnology for Biofuels and Bioproducts 2022 15:142
  10. Construction of efficient microbial cell factories is one of the core steps for establishing green bio-manufacturing processes. However, the complex metabolic regulation makes it challenging in driving the met...

    Authors: Ning Gao, Jiaoqi Gao, Wei Yu, Sijia Kong and Yongjin J. Zhou
    Citation: Biotechnology for Biofuels and Bioproducts 2022 15:141
  11. The budding yeast Komagataella phaffii (Pichia pastoris) is widely employed to secrete proteins of academic and industrial interest. For secretory proteins, signal peptides are the sorting signal to direct protei...

    Authors: Chenwei Zou, Lingfang Lu, Shengyan Wang, Chenshan Zhang, Xuequn Chen, Yao Lin and Yide Huang
    Citation: Biotechnology for Biofuels and Bioproducts 2022 15:140
  12. Itaconic acid is a promising platform chemical for a bio-based polymer industry. Today, itaconic acid is biotechnologically produced with Aspergillus terreus at industrial scale from sugars. The production of fue...

    Authors: Marc Schmollack, Felix Werner, Janine Huber, Dirk Kiefer, Manuel Merkel, Rudolf Hausmann, Daniel Siebert and Bastian Blombach
    Citation: Biotechnology for Biofuels and Bioproducts 2022 15:139
  13. 1,3-β-glucan is a polysaccharide widely distributed in the cell wall of several phylogenetically distant organisms, such as bacteria, fungi, plants and microalgae. The presence of highly active 1,3-β-glucanase...

    Authors: Valentina Scafati, Francesca Troilo, Sara Ponziani, Moira Giovannoni, Anna Scortica, Daniela Pontiggia, Francesco Angelucci, Adele Di Matteo, Benedetta Mattei and Manuel Benedetti
    Citation: Biotechnology for Biofuels and Bioproducts 2022 15:138
  14. With the increasing need for microbial bioproduction to replace petrochemicals, it is critical to develop a new industrial microbial workhorse that improves the conversion of lignocellulosic carbon to biofuels...

    Authors: Xi Wang, Edward E. K. Baidoo, Ramu Kakumanu, Silvia Xie, Aindrila Mukhopadhyay and Taek Soon Lee
    Citation: Biotechnology for Biofuels and Bioproducts 2022 15:137
  15. The conversion of lignin-derived aromatic monomers into valuable chemicals has promising potential to improve the economic competitiveness of biomass biorefineries. Pinosylvin is an attractive pharmaceutical w...

    Authors: Yueli Hu, Chen Zhang, Lihua Zou, Zhaojuan Zheng and Jia Ouyang
    Citation: Biotechnology for Biofuels and Bioproducts 2022 15:136
  16. The Carbohydrate-Active enZymes (CAZy) auxiliary activity family 3 (AA3) comprises flavin adenine dinucleotide-dependent (FAD) oxidoreductases from the glucose–methanol–choline (GMC) family, which play auxilia...

    Authors: Hongbo Zhao, Johanna Karppi, Thi Truc Minh Nguyen, Annie Bellemare, Adrian Tsang, Emma Master and Maija Tenkanen
    Citation: Biotechnology for Biofuels and Bioproducts 2022 15:135
  17. Simultaneous saccharification and fermentation (SSF) is effective for minimizing sugar inhibition during high solids fermentation of biomass solids to ethanol. However, fungal enzymes used during SSF are optim...

    Authors: Priya Sengupta, Ramya Mohan, Ian Wheeldon, David Kisailus, Charles E. Wyman and Charles M. Cai
    Citation: Biotechnology for Biofuels and Bioproducts 2022 15:134
  18. Anthocyanins are metabolites of phenylpropanoid pathway, and involves in diverse processes of plant development and adaptation, which are regulated by the MYB-bHLH-WD40 (MBW) protein complexes. Many R2R3-MYB a...

    Authors: Tao Xie, Xiongyun Zan, Xin Chen, Haotian Zhu, Hao Rong, Youping Wang and Jinjin Jiang
    Citation: Biotechnology for Biofuels and Bioproducts 2022 15:133
  19. In the process of cellulose hydrolysis, carbohydrate hydrolysates are transported into cells through membrane transporters, and then affect the expression of cellulase-encoding genes. Sugar transporters play a...

    Authors: Haiyan Wang, Ai-Ping Pang, Wei Wang, Bingzhi Li, Chengcheng Li, Fu-Gen Wu and Fengming Lin
    Citation: Biotechnology for Biofuels and Bioproducts 2022 15:132
  20. The marine diatom Phaeodactylum tricornutum is a commercially viable species due to its bioactive substances and lipid productivity. Increasing attention has been paid to the isolation or genetic modification of ...

    Authors: Shan Gao, Lu Zhou, Wenting Yang, Lijun Wang, Xuehua Liu, Yingchun Gong, Qiang Hu and Guangce Wang
    Citation: Biotechnology for Biofuels and Bioproducts 2022 15:131
  21. Bioenergy plays a significant role in the green transition. In this work, the conversion of methanol and mutton bone fat oil (as a low-cost feedstock) for bioenergy production was studied. The five-level, thre...

    Authors: Ali Farokhnia, Seyyed Mohammad Jokar, Payam Parvasi and Albert S. Kim
    Citation: Biotechnology for Biofuels and Bioproducts 2022 15:130
  22. C-glycosylated flavonoids are a main type of structural modification and can endow flavonoids with greater stability, bioactivity, and bioavailability. Although some C-glycosylated flavonoids have been biosynthes...

    Authors: Yangbao Wu, Huan Wang, Yang Liu, Linguo Zhao and Jianjun Pei
    Citation: Biotechnology for Biofuels and Bioproducts 2022 15:129
  23. A total of 398 kt of pasta waste (PW), generated during the production process of pasta, were produced in 2021. Due to its chemical composition and practically zero cost, PW has already been studied as a raw m...

    Authors: Cristina Marzo-Gago, Joachim Venus and José Pablo López-Gómez
    Citation: Biotechnology for Biofuels and Bioproducts 2022 15:128
  24. Primary degraders of polysaccharides play a key role in anaerobic biotopes, where plant cell wall accumulates, providing extracellular enzymes to release fermentable carbohydrates to fuel themselves and other ...

    Authors: Nian Liu, Séverine Gagnot, Yann Denis, Deborah Byrne, Craig Faulds, Henri-Pierre Fierobe and Stéphanie Perret
    Citation: Biotechnology for Biofuels and Bioproducts 2022 15:127
  25. The strategy of synergistic application of biological and chemical catalysis is an important approach for efficiently converting renewable biomass into chemicals and fuels. In particular, the method of determi...

    Authors: Hsi-Hsin Lin, Daniel Mendez‐Perez, Jimin Park, Xi Wang, Yan Cheng, Jiajie Huo, Aindrila Mukhopadhyay, Taek Soon Lee and Brent H. Shanks
    Citation: Biotechnology for Biofuels and Bioproducts 2022 15:126
  26. Biological conversion of the surplus of renewable electricity and carbon dioxide (CO2) from biogas plants to biomethane (CH4) could support energy storage and strengthen the power grid. Biological methanation (BM...

    Authors: Hoda Khesali Aghtaei, Sebastian Püttker, Irena Maus, Robert Heyer, Liren Huang, Alexander Sczyrba, Udo Reichl and Dirk Benndorf
    Citation: Biotechnology for Biofuels and Bioproducts 2022 15:125
  27. Microbial fuel cells (MFCs) are among the leading research topics in the field of alternative energy sources due to their multifunctional potential. However, their low bio-energy production rate and unstable p...

    Authors: Imologie Meshack Simeon, Alfons Weig and Ruth Freitag
    Citation: Biotechnology for Biofuels and Bioproducts 2022 15:124
  28. Polyunsaturated fatty acid (PUFA) synthase is a multi-domain mega-enzyme that effectively synthesizes a series of PUFAs in marine microorganisms. The dehydratase (DH) domain of a PUFA synthase plays a crucial ...

    Authors: Bihan Chen, Feng Wang, Xi Xie, Huifan Liu, Dongjie Liu, Lukai Ma, Gengsheng Xiao and Qin Wang
    Citation: Biotechnology for Biofuels and Bioproducts 2022 15:123
  29. Microalgae, with their high adaptability to various stress conditions and rapid growth, are considered excellent biomass resources for lipid production and biodiesel feedstocks. However, lipid yield and produc...

    Authors: Mostafa E. Elshobary, Hossain M. Zabed, Xianghui Qi and Rania A. El-Shenody
    Citation: Biotechnology for Biofuels and Bioproducts 2022 15:122
  30. Plant cell walls represent the most plentiful renewable organic resource on earth, but due to their heterogeneity, complex structure and partial recalcitrance, their use as biotechnological feedstock is still ...

    Authors: Yajing Liu, Angel Angelov, Werner Feiler, Melanie Baudrexl, Vladimir Zverlov, Wolfgang Liebl and Sonja Vanderhaeghen
    Citation: Biotechnology for Biofuels and Bioproducts 2022 15:121
  31. Escherichia coli have both the Embden–Meyerhof–Parnas pathway (EMPP) and Entner–Doudoroff pathway (EDP) for glucose breakdown, while the EDP primarily remains inactive for glucose metabolism. However, EDP is a mo...

    Authors: Ye Eun Kim, Kyung Hyun Cho, Ina Bang, Chang Hee Kim, Young Shin Ryu, Yuchan Kim, Eun Mi Choi, Linh Khanh Nong, Donghyuk Kim and Sung Kuk Lee
    Citation: Biotechnology for Biofuels and Bioproducts 2022 15:120
  32. Woody plants provide the most abundant biomass resource that is convertible for biofuels. Since lignin is a crucial recalcitrant factor against lignocellulose hydrolysis, genetic engineering of lignin biosynth...

    Authors: Chunfen Fan, Wenyi Zhang, YuHao Guo, Kuan Sun, Lijun Wang and Keming Luo
    Citation: Biotechnology for Biofuels and Bioproducts 2022 15:119
  33. Bacterial lignin degradation is believed to be primarily achieved by a secreted enzyme system. Effects of such extracellular enzyme systems on lignin structural changes and degradation pathways are still not c...

    Authors: Zhangyang Xu, Bo Peng, Reta Birhanu Kitata, Carrie D. Nicora, Karl K. Weitz, Yunqiao Pu, Tujin Shi, John R. Cort, Arthur J. Ragauskas and Bin Yang
    Citation: Biotechnology for Biofuels and Bioproducts 2022 15:117
  34. Developing economically viable pathways to produce renewable energy has become an important research theme in recent years. Lignocellulosic biomass is a promising feedstock that can be converted into second-ge...

    Authors: Sarvada Chipkar, Katherine Smith, Elizabeth M. Whelan, Derek J. Debrauske, Annie Jen, Katherine A. Overmyer, Andrea Senyk, Larkin Hooker-Moericke, Marissa Gallmeyer, Joshua J. Coon, A. Daniel Jones, Trey K. Sato and Rebecca G. Ong
    Citation: Biotechnology for Biofuels and Bioproducts 2022 15:116
  35. Microalgae can absorb CO2 during photosynthesis, which causes the aquatic environmental pH to rise. However, the pH is reduced when microalga Euglena gracilis (EG) is cultivated under photoautotrophic conditions....

    Authors: Mingcan Wu, Guimei Wu, Feimiao Lu, Hongxia Wang, Anping Lei and Jiangxin Wang
    Citation: Biotechnology for Biofuels and Bioproducts 2022 15:115
  36. Schizochytrium sp. is a heterotrophic, oil-producing microorganism that can efficiently produce lipids. However, the industrial production of bulk chemicals using Schizochytrium sp. is still not economically viab...

    Authors: Ling-Ru Wang, Zi-Xu Zhang, Fang-Tong Nong, Jin Li, Peng-Wei Huang, Wang Ma, Quan-Yu Zhao and Xiao-Man Sun
    Citation: Biotechnology for Biofuels and Bioproducts 2022 15:114
  37. Saccharomyces cerevisiae is intensively used for industrial ethanol production. Its native fermentation pathway enables a maximum product yield of 2 mol of ethanol per mole of glucose. Based on conservation laws,...

    Authors: Aafke C. A. van Aalst, Robert Mans and Jack T. Pronk
    Citation: Biotechnology for Biofuels and Bioproducts 2022 15:112
  38. As one of the most important staple food crops, rice produces large of agronomic biomass residues that contain lots of secondary cell walls (SCWs). Membrane trafficking plays key roles in SCWs biosynthesis, bu...

    Authors: Hongrui Jiang, Yan Ren, Junyao Guo, Huijie Yang, Xiaotong Zhu, Wenhao Li, Liangzhi Tao, Yue Zhan, Qi Wang, Yuejin Wu, Binmei Liu and Yafeng Ye
    Citation: Biotechnology for Biofuels and Bioproducts 2022 15:111
  39. The robust model cyanobacterium Synechocystis PCC 6803 is increasingly explored for its potential to use solar energy, water and atmospheric CO2 for the carbon-neutral production of terpenes, the high-value chemi...

    Authors: Victoire Blanc-Garin, Célia Chenebault, Encarnación Diaz-Santos, Marine Vincent, Jean-François Sassi, Corinne Cassier-Chauvat and Franck Chauvat
    Citation: Biotechnology for Biofuels and Bioproducts 2022 15:110
  40. Biological catalysis is an important approach for the production of high-value-added compounds, especially for products with complex structures. Limited by the complex steps of chemical synthesis and low yield...

    Authors: Zheyi Wang, Yan Zeng, Hongmin Jia, Niping Yang, Mengshuang Liu, Mingyue Jiang and Yanning Zheng
    Citation: Biotechnology for Biofuels and Bioproducts 2022 15:109
  41. Metabolic rewiring in microbes is an economical and sustainable strategy for synthesizing valuable natural terpenes. Terpenes are the largest class of nature-derived specialized metabolites, and many have valu...

    Authors: So-Hee Son, Jae-Eung Kim, Soo Young Moon, In-Seung Jang, Byung Jo Yu and Ju Young Lee
    Citation: Biotechnology for Biofuels and Bioproducts 2022 15:108
  42. The dramatic increase in greenhouse gas (GHG) emissions, which causes serious global environmental issues and severe climate changes, has become a global problem of concern in recent decades. Currently, native...

    Authors: Bobo Liang, Rongzhan Fu, Yingqun Ma, Lizhen Hu, Qiang Fei and Xin-Hui Xing
    Citation: Biotechnology for Biofuels and Bioproducts 2022 15:107
  43. Lignin is a promising alternative to traditional fossil resources for producing biofuels due to its aromaticity and renewability. Pyrolysis is an efficient technology to convert lignin to valuable chemicals, w...

    Authors: Xinyu Lu and Xiaoli Gu
    Citation: Biotechnology for Biofuels and Bioproducts 2022 15:106
  44. Lipoxygenase (EC. 1.13.11.12, LOX) can catalyze the addition of oxygen into polyunsaturated fatty acids to produce hydroperoxides, which are widely used in the food, chemical, and pharmaceutical industries. In...

    Authors: Cuiping Pang, Guoqiang Zhang, Song Liu, Jingwen Zhou, Jianghua Li and Guocheng Du
    Citation: Biotechnology for Biofuels and Bioproducts 2022 15:105
  45. Terpenes are one of the most diverse and abundant classes of natural biomolecules, collectively enabling a variety of therapeutic, energy, and cosmetic applications. Recent genomics investigations have predict...

    Authors: Suryang Kwak, Nathan Crook, Aki Yoneda, Naomi Ahn, Jie Ning, Jiye Cheng and Gautam Dantas
    Citation: Biotechnology for Biofuels and Bioproducts 2022 15:104
  46. In oleaginous yeast, nitrogen limitation is a critical parameter for lipid synthesis. GATA-family transcriptional factor GAT1, a member of the target of rapamycin (TOR) pathway and nitrogen catabolite repressi...

    Authors: Yulu Ran, Hui Xu, Qingzhuoma Yang, Yi Xu, Huahao Yang, Dairong Qiao and Yi Cao
    Citation: Biotechnology for Biofuels and Bioproducts 2022 15:103
  47. Microalgae protein is considered as a sustainable alternative to animal protein in the future. Using waste for microalgal culture can upgrade low-value raw materials into high-value products, helping to offset...

    Authors: Yihui Cai, Ligong Zhai, Xiaoman Fang, Kangping Wu, Yuhuan Liu, Xian Cui, Yunpu Wang, Zhigang Yu, Roger Ruan, Tongying Liu and Qi Zhang
    Citation: Biotechnology for Biofuels and Bioproducts 2022 15:102
  48. β-Farnesene is a sesquiterpene with versatile industrial applications. The production of β-farnesene from waste lipid feedstock is an attractive method for sustainable production and recycling waste oil. Yarrowia...

    Authors: Yinghang Liu, Jin Zhang, Qingbin Li, Zhaoxuan Wang, Zhiyong Cui, Tianyuan Su, Xuemei Lu, Qingsheng Qi and Jin Hou
    Citation: Biotechnology for Biofuels and Bioproducts 2022 15:101